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Publications

A selection of publications featuring Cubresa’s PET insert technology.

2019

Adlimoghaddam A, Snow W, Stortz G, Perez C, Djordjevic J, Goertzen AL, Ko JH, and Albensi BC. Regional hypometabolism in the 3xTg mouse model of Alzheimer’s disease. Neurobiology of Disease. 2019 March 14; 127: 267-277. doi: https://doi.org/10.1016/j.nbd.2019.03.008

Van Elburg D, Shrestha R, and Goertzen AL. Towards a second-generation PET/MR insert with enhanced timing and count rate performance. Physics in Medicine and Biology. 2019 Mar 12. doi: https://doi.org/10.1088/1361-6560/ab0efa

2018

Goldenberg JM, Cárdenas-Rodríguez J, Pagel MD. Preliminary Results that Assess Metformin Treatment in a Preclinical Model of Pancreatic Cancer Using Simultaneous [18 F] FDG PET and acidoCEST MRI. Molecular Imaging and Biology. 2018 Aug 1;20(4):575-83. doi: https://doi.org/10.1007/s11307-018-1164-4

2017

Stortz G, Thiessen JD, Bishop D, Khan MS, Kozlowski P, Retière F, Schellenberg G, Shams E, Zhang X, Thompson CJ, Goertzen AL. Performance of a PET Insert for High-Resolution Small-Animal PET/MRI at 7 Tesla. Journal of Nuclear Medicine. 2018 Mar 1;59(3):536-42. doi: https://doi.org/10.2967/jnumed.116.187666

Goertzen AL, Shrestha R, Khan MS, Stortz G, Bishop D, Kozlowski P, Retière F, Thiessen JD, Thompson CJ, Sossi V. Data Acquisition for a Preclinical MR Compatible PET Insert using the OpenPET Platform. IEEE Transactions on Radiation and Plasma Medical Sciences. 2017 Nov;1(6):495-504. doi: https://doi.org/10.1109/TRPMS.2017.2747407

2016

Thiessen JD, Shams E, Stortz G, Schellenberg G, Bishop D, Khan MS, Kozlowski P, Retière F, Sossi V, Thompson CJ, Goertzen AL. MR-Compatibility of a High-Resolution Small Animal PET Insert Operating inside a 7 T MRI. Physics in Medicine & Biology. 2016 Oct 25;61(22):7934. doi: https://doi.org/10.1088/0031-9155/61/22/7934

Goertzen AL, Stortz G, Thiessen JD, Bishop D, Khan MS, Kozlowski P, Retière F, Schellenberg G, Shams E, Sossi V, Thompson CJ. First Results from a High-Resolution Small Animal SiPM PET Insert for PET/MR Imaging at 7T. IEEE Transactions on Nuclear Science. 2016 Oct;63(5):2424-33. doi: https://doi.org/10.1109/TNS.2016.2576963

Schellenberg G, Stortz G, Goertzen AL. An Algorithm for Automatic Crystal Identification in Pixelated Scintillation Detectors using Thin Plate Splines and Gaussian Mixture Models. Physics in Medicine & Biology. 2016 Jan 21;61(3):N90. doi: https://doi.org/10.1088/0031-9155/61/3/n90

2014

Thompson C, Goertzen A, Thiessen J, Bishop D, Stortz G, Kozlowski P, Retière F, Zhang X, Sossi V. Development of a PET Scanner for Simultaneously Imaging Small Animals with MRI and PET. Sensors. 2014 Aug;14(8):14654-71. doi: https://dx.doi.org/10.3390/s140814654

Shams E, Thiessen JD, Bishop D, Kozlowski P, Retière F, Khan MS, Sossi V, Stortz G, Thompson CJ, Goertzen AL. Evaluation of Performance and Stability of an MR Compatible PET Detector. In 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC). 2014 Nov 8 (pp. 1-4). doi: https://doi.org/10.1109/NSSMIC.2014.7431008

2013

Stortz G, Walker MD, Thompson CJ, Goertzen AL, Retiere F, Zhang X, Thiessen JD, Kozlowski P, Sossi V. Characterization of a New MR Compatible Small Animal PET Scanner using Monte-Carlo Simulations. IEEE Transactions on Nuclear Science. 2013 Jun;60(3):1637-44. doi: https://doi.org/10.1109/TNS.2013.2256927

Goertzen AL, Zhang X, McClarty MM, Berg EJ, Liu CY, Kozlowski P, Retière F, Ryner L, Sossi V, Stortz G, Thompson CJ. Design and Performance of a Resistor Multiplexing Readout Circuit for a SiPM Detector. IEEE Transactions on Nuclear Science. 2013 Jun;60(3):1541-9. doi: https://doi.org/10.1109/TNS.2013.2251661

Thompson CJ, Goertzen AL, Kozlowski P, Retière F, Stortz G, Sossi V, Zhang X. Measurement of Energy and Timing Resolution of Very Highly Pixellated LYSO Crystal Blocks with Multiplexed SiPM Readout for use in a Small Animal PET/MR Insert. In 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC). 2013 Oct 27 (pp. 1-5). doi: https://doi.org/10.1109/NSSMIC.2013.6829134

Zhang X, Thompson CJ, Thiessen JD, Goertzen AL. Simulation Studies of a Phoswich PET Detector Design with a Two-Fold Improvement in Spatial Sampling. In 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC). 2013 Oct 27 (pp. 1-4). doi: https://doi.org/10.1109/NSSMIC.2013.6829093

Thiessen JD, Jackson C, O'Neill K, Bishop D, Kozlowski P, Retière F, Shams E, Stortz G, Thompson CJ, Goertzen AL. Performance Evaluation of SensL SiPM Arrays for High-Resolution PET. In 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC). 2013 Oct 27 (pp. 1-4). doi: https://doi.org/10.1109/NSSMIC.2013.6829093

Shams E, Thiessen JD, Bishop D, Kozlowski P, Retière F, Sossi V, Stortz G, Thompson CJ, Goertzen AL. A PET Detector Interface Board and Slow Control System Based on the Raspberry Pi®. In 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference (2013 NSS/MIC). 2013 Oct 27 (pp. 1-3). doi: https://doi.org/10.1109/NSSMIC.2013.6829202

Zhang X, Stortz G, Sossi V, Thompson CJ, Retière F, Kozlowski P, Thiessen JD, Goertzen AL. Development and Evaluation of a LOR-based Image Reconstruction with 3D System Response Modeling for a PET Insert with Dual-Layer Offset Crystal Design. Physics in Medicine & Biology. 2013 Nov 11;58(23):8379. doi: https://doi.org/10.1088/0031-9155/58/23/8379