Development of Applications of PET/MR

Melanie Martin PhD, Director, Magnetic Resonance Microscopy Centre, Co-Director, The University of Winnipeg Brain Imaging and Metabolic Research Lab, University of Winnipeg

Katinka Stecina Ph.D., Assistant Professor, Department of Physiology and Pathophysiology, Rady Faculty of Health Sciences, University of Manitoba.

We are developing and optimizing PET/MR imaging tools in order to study neuroscience. We aim to find the relationship between hemodynamics and glucose metabolism in the brain and to understand why different imaging methods do not provide activation in the same brain areas for certain stimulations. We plan to demonstrate excitation of certain neurons using PET/MR in combination with chemogenetic (designer receptor-based) methods.

We also aim to develop higher resolution MR techniques for inferences of sizes of anatomical structures in the brain, and to use these images to better quantify PET images.