NuPET™ Insert

MRI-Compatible Preclinical PET Scanner

NuPET MR-compatible PET scanner
The Cubresa NuPET™ MR-compatible PET scanner goes into the bore of an existing MRI instrument. The NuPET scanner can be easily inserted or removed in minutes and enables simultaneous preclinical molecular and functional imaging.

Discover links between molecular mechanisms and functional response

Cubresa’s NuPET™ is a revolutionary in-bore PET scanner that inserts into existing MRI instruments to create a powerful and flexible hybrid preclinical in vivo imaging platform that combines the molecular sensitivity of PET with the superior anatomical, structural, and functional information of MRI.

Researchers using simultaneous PET/MRI imaging can measure multiple physiological processes concurrently with exceptional tissue contrast, quantitative accuracy, and study throughput.

Sequential PET/MRI scanning captures data at different times, making it difficult to analyze important functional relationships when animal physiology can change within minutes. With NuPET’s simultaneous scanning, PET and MRI work in unison to capture time-synchronized and highly complementary information previously unattainable – so you can trailblaze a path to new discoveries. Shorter anesthesia duration also helps minimize animal stress and reduce the risk of inducing physiological changes that can affect study quality.

Cubresa NuPET MR-compatible PET scanner being inserted into a preclinical MRI bore
Cubresa’s NuPET MR-compatible PET scanner is shown being inserted into the bore of a preclinical MRI.

The NuPET Solution

NuPET systems come in two sizes, the NuPET 66 and NuPET 200, to accommodate a variety of animal models including rodents, rabbits, and non-human primates (NHPs).

The NuPET scanner can be quickly inserted and removed when simultaneous PET/MRI imaging is required. However, should only PET imaging be needed, the NuPET systems can be used as stand-alone scanners. This table-top option ensures that use of the MR is not restricted when only PET scanning is required, offering institutions flexibility and convenience.


  • MR Compatible design and true simultaneous PET/MRI data acquisition
  • Supports powerful small animal gradients in a wide range of MRI systems at various field strengths
  • State of the art PET technology delivers high spatial resolution and sensitivity
  • Automatic PET/MRI co-registration
  • Intuitive acquisition & reconstruction software
  • Rapid setup time and fast removal with no modifications to the MRI system
  • Stand-alone PET imaging option for maximum flexibility and utilization

Data Sheets

Reveal Disease & Therapeutic Mechanisms with Simultaneous Molecular & Functional Imaging

Non-invasively generate 3D images of biochemical processes in live animals with Cubresa’s in-bore NuPET™ Positron Emission Tomography (PET) imaging system for your existing preclinical Magnetic Resonance Imaging (MRI) system. Add precisely registered molecular imaging to high-resolution anatomic imaging with simultaneous PET/MR imaging.

An Easy Addition to Your Small-Animal Preclinical MRI System

Advanced solid-state, chip-based detectors optimized for small-animal subjects preserve important performance parameters such as spatial resolution and sensitivity. With the industry’s most compact footprint, Cubresa’s PET scanner integrates with existing preclinical MRI systems to deliver simultaneous PET/MR imaging without impacting standalone MRI performance.

The NuPET Insert System

Incredibly flexible, the NuPET system can be used in multiple MRIs within a research lab. Completely mobile, the insert can be moved and inserted into various systems as required. This feature enables research groups to share equipment and move NuPET across the lab, down the hall, or to another building. Alternatively, NuPET can also be used as a stand-alone PET imaging system, when simultaneous imaging is not required.

Learn More about Cubresa NuPET Preclinical Scanner

Research Highlights

Learn how Cubresa’s customers are using the power of NuPET technology to enhance their research in a variety of application areas.

Scientific Publications

Follow this link for a selection of publications featuring studies using NuPET technology.

Image and Poster Gallery

Learn more about our client’s leading-edge research through posters and images.